Unraveling the cytotoxicity and metabolic pathways of binary natural deep eutectic solvent systems
نویسندگان
چکیده
منابع مشابه
Unraveling the cytotoxicity and metabolic pathways of binary natural deep eutectic solvent systems
In this study, the anticancer potential and cytotoxicity of natural deep eutectic solvents (NADESs) were assessed using HelaS3, PC3, A375, AGS, MCF-7, and WRL-68 hepatic cell lines. NADESs were prepared from choline chloride, fructose, or glucose and compared with an N,N-diethyl ethanolammonium chloride:triethylene glycol DES. The NADESs (98 ≤ EC50 ≥ 516 mM) were less toxic than the DES (34 ≤ E...
متن کاملEfficient Synthesis of Dihydropyrimidine and Amidoalkyl Naphthol Derivatives Using Zinc Chloride-Based Deep Eutectic Systems as Solvent & Catalyst
Dihydropyrimidine and amidoalkyl naphthol derivatives have been prepared efficiently in a one-pot synthesis using ZnCl2/urea and ZnCl2/acetamide deep eutectic systems as reaction medium and homogeneous catalyst. This method offers some advantages such as simple procedure, inexpensive solvent and catalyst and good yields of the final products in short reaction times. The use of non-toxic and env...
متن کاملNatural deep eutectic solvents: cytotoxic profile
The purpose of this study was to investigate the cytotoxic profiles of different ternary natural deep eutectic solvents (NADESs) containing water. For this purpose, five different NADESs were prepared using choline chloride as a salt, alongside five hydrogen bond donors (HBD) namely glucose, fructose, sucrose, glycerol, and malonic acid. Water was added as a tertiary component during the eutect...
متن کاملApplication of natural deep eutectic solvents for extraction of
Natural deep eutectic solvents (NADESs) considered as “green” solvents offer an efficient, safe, sustainable, and cost effective method alternative to conventional extraction while microwave assisted extraction (MAE) is a convenient, rapid, environmental friendly and efficient technique. The combination of NADESs with MAE was applied in this study for the recovery of phenolic compounds from oli...
متن کاملBroad range chemical profiling of natural deep eutectic solvent extracts using a high performance thin layer chromatography-based method.
Natural deep eutectic solvents (NADES) made mainly with abundant primary metabolites are being increasingly applied in green chemistry. The advantages of NADES as green solvents have led to their use in novel green products for the food, cosmetics and pharma markets. However, one of the main difficulties encountered in the development of novel products and their quality control arises from thei...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep41257